ISSN 1662-4009 (online)

ey0018.4-9 | New Perspectives | ESPEYB18

4.9. Prospective longitudinal assessment of linear growth and adult height in female adolescents with anorexia nervosa

D Modan-Moses , A Yaroslavsky , O Pinhas-Hamiel , Y Levy-Shraga , B Kochavi , S Iron-Segev , A Enoch-Levy , A Toledano , D Daniel Stein

J Clin Endocrinol Metab. 2021;106(1):e1–e10. doi: 10.1210/clinem/dgaa510. PMID: 32816013This prospective observational study on a cohort of 255 adolescents with anorexia nervosa (AN) aimed to investigate the effects of nutritional restriction on linear growth and adult height. Whereas premorbid height did not differ from reference standards, girls with AN showed a mild but significantl...

ey0018.14-10 | (1) | ESPEYB18

14.10. Corticosterone inhibits GAS6 to govern hair follicle stem-cell quiescence

Choi Sekyu , Zhang Bing , Ma Sai , Gonzalez-Celeiro Meryem , Stein Daniel , Jin Xin , Kim Seung Tea , Kang Yuan-Lin , Besnard Antoine , Rezza Amelie , Grisanti Laura , Buenrostro Jason D , Rendl Michael , Nahrendorf Matthias , Sahay Amar , Hsu Ya-Chieh

Nature 2021; 592: 428–432https://www.nature.com/articles/s41586-021-03417-2These authors report that in mice the stress hormone corticosterone (the rodent equivalent of cortisol in humans) acts on dermal papillae to suppress expression of Gas6 (encoding growth arrest specific 6) and thereby cause hair follicle stem cell (HFSC) quiescence and reduced hair growth. They show that...